“Teen Mom 2″ Star Leah Messer Suffers Miscarriage
Leah Messer, who stars as the young mom of twins on reality show “Teen Mom 2″, has suffered a miscarriage. Just weeks ago, Leah announced [...]
“Teen Mom 2″ Star Leah Messer Suffers Miscarriage Stupid Celebrities Gossip Stupid Celebrities Gossip News
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STATE COLLEGE, Pa. ? They stood outside for hours on a winter afternoon, waiting to pay their respects to the late Joe Paterno. The line snaked down a long block on the Penn State campus.
Inside a campus spiritual center, the coach's body lay in a closed, hardwood casket topped by a spray of white roses. About six feet away sat a stylized black-and-white picture of the man who became lovingly known on campus as "JoePa," smiling and peering out through his trademark thick-rimmed glasses.
Three days of public mourning began Tuesday for a Penn State community already racked by months of turmoil. The 85-year-old Paterno ? a Hall of Fame coach and the face of the university ? died Sunday of lung cancer. He had been ousted just days before learning of his diagnosis in November, forced out of his job in the wake of child sex-abuse charges against a former assistant.
"We're not going to focus on the bad, we're going to pull together and focus on the good," said Brittany Yingling, 23, of Altoona, donning a blue Penn State knit cap with "Paterno" in bold white letters emblazoned on the front. "He's going to leave a lasting legacy on so many people."
And thousands showed up, lining a main campus artery for a chance to make the walk, single file, past Paterno's casket, which had an "honor guard" of two Penn State players ? one past and one present. Some mourners stopped for a moment of reflection, or to genuflect in the interfaith hall.
Others fought back tears and sniffles. The only other sounds were the clicks from media photographers, taking occasional pictures.
Jay Paterno, one of the coach's sons, was still shaking hands with the well-wishers when police shut down the visitation at 10:45 p.m. EST, telling a handful of people on their way in that they could come back early Wednesday morning.
Paterno won 409 games and two national championships over his 46-year career admired by peers as much for its longevity as its success. Paterno also took as much pride in the program's graduation rates, often at or close to the top of the Big Ten.
"I came to pay my respects to a great man, that has nothing to do with victories," said Paterno's longtime assistant and defensive coordinator, Tom Bradley. "A lot of his victories people don't even know about."
Large windows bathed the white-walled hall at the Pasquerilla Spiritual Center in light on a cloudy day. Some of Paterno's family attend services at the center.
Members of the public were preceded by the family, including two of Paterno's sons. Scott Paterno and Jay ? the former Nittany Lions quarterback coach ? thanked many of the visitors before they exited the building.
"Going in there, waiting two hours in line, it was worth every second of it," said Rob Gressinger, a Penn State junior. "I've lost all my grandparents and the feeling is the exact same thing ... Feels like you lost one of your own."
Also paying respects privately Tuesday morning were former and current players and coaches. Members of the current team wore dark suits and arrived in three blue Penn State buses, the same ones that once carried Paterno and the team to games at Beaver Stadium on fall Saturdays.
Among the former players was Mike McQueary. As a graduate assistant to Paterno in 2002, he went to the coach saying he had witnessed former defensive coordinator Jerry Sandusky assaulting a boy in the shower at the Penn State football building. Paterno relayed that to his bosses ? including the head of campus police ? but university trustees felt he should have done more, and it played into their decision to oust the longtime coach on Nov. 9. That came four days after Sandusky was charged with child sex-abuse counts.
Dressed in a blue coat and tie with a white shirt, the school colors, McQueary was among those at an event that stretched well into Tuesday night. McQueary declined comment after leaving the viewing.
Earlier Tuesday, former Penn State and Pittsburgh Steelers great Franco Harris, a vocal critic of the university trustees, also came to say goodbye. Others included NFL receivers Deon Butler and Jordan Norwood, Norwood's father and Baylor assistant coach Brian Norwood and former quarterback Daryll Clark ? who also served as an honor guard.
Texans receiver Bryant Johnson, a nine-year NFL veteran, said he decided to attend Penn State out of high school in Baltimore because "he wanted to play for a legendary coach."
"I wanted to play for someone that instilled the values that he believed in," Johnson said. "I wanted to play for someone who believed in guys graduating."
Paterno was beloved as much by others in the community for his philanthropic efforts, such as donating millions back to the university for projects including the campus library bearing the family name. Paterno Library sits a short walk across the street from the spiritual center.
"He did so much for this town and school and the students. It wasn't all football," said Martha Edwards of Jersey Shore, Pa. She isn't a graduate but decided to attend anyway.
"Right over there is the library with his name on it," she said. "Nobody comes any better than him."
There is another public viewing Wednesday at the interfaith center, and after that Paterno's family will hold a private funeral and procession through State College.
On Thursday, the school's basketball arena will be the site of a public service called "A Memorial for Joe." Tickets were quickly snapped up for the event, even though there was a two-per-person limit for those ordering.
___
Associated Press writer Mark Scolforo contributed to this report.
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KABUL, Afghanistan ? The Taliban must renounce ties to terrorists and endorse peace efforts as a condition for opening a political office in the Gulf state of Qatar, a senior U.S. diplomat said Sunday.
Marc Grossman, the special U.S. envoy to Afghanistan and Pakistan, called for quick work in setting up the office in Qatar, seen as a step to negotiating an end to the decade-long war in Afghanistan between the Taliban and the Western-backed government.
The issue underscores the complexity of efforts to wind down the war ahead of the scheduled departure of NATO combat forces by the end of 2014. Publicly, the Taliban have expressed no interest in reconciliation, and while the U.S. says repeatedly that the peace process must be led by Afghans, Kabul continues to fear it is being left out of the negotiating process.
Grossman spoke to reporters Sunday in Kabul alongside Afghanistan's Deputy Foreign Minister Jawed Ludin.
Grossman said Qatar and Afghanistan need to be in direct contact about the office, but "for an office to open, we also need to have a clear statement by the Afghan Taliban against international terrorism and in support of a peace process to end the armed conflict in Afghanistan."
Grossman, speaking at the Afghan Foreign Ministry on a snowy evening in Kabul, noted that the Afghan government would welcome a delegation from Qatar to discuss setting up the office.
Reassuring Afghan President Hamid Karzai, who fears he is being sidelined by U.S. efforts to find a political resolution to the war, Grossman said, "Only Afghans can decide the future of Afghanistan."
Before making his first visit to Afghanistan, Grossman made stops in Turkey, Saudi Arabia, the United Arab Emirates and India. He wanted to stop in Pakistan as well, but he said Pakistani officials did not want to meet with him now because they were still revising their policy toward the U.S.
The relationship is badly strained over the U.S. unilateral raid in Pakistan that killed al-Qaida leader Osama bin Laden and a U.S. airstrike late last year that killed 24 Pakistan soldiers. Pakistan, where many Afghan insurgent leaders are said to be based, has closed overland routes into Afghanistan for U.S. and NATO war supplies.
Both Grossman and Ludin said Pakistan has a crucial role to play in efforts to craft a peace deal with the Taliban.
"There really can't be a comprehensive settlement here ? a peace process ? unless Pakistan is part of it," Grossman said.
Last year Washington opened secret negotiations with the Taliban exploring their willingness to enter into peace talks ahead of the withdrawal of U.S. troops.
Talks with the Taliban briefly faltered last summer after Karzai learned of the clandestine negotiations and made them public, temporarily scuttling them. Privately, Karzai has expressed fears that the United States will broker a deal with the Taliban that will be imposed on his government.
U.S. conversations with Taliban representatives have focused on establishing the Taliban office in Qatar and prisoner exchanges. The Taliban are seeking the release of five prisoners from the U.S. military prison in Guantanamo Bay, Cuba, including Khairullah Khairkhwa, the former governor of Herat province, and Mullah Mohammed Fasl, a top Taliban commander.
Ludin expressed the Afghan government's support in getting a Taliban political office opened in Qatar and said it also would back an American decision to transfer some Taliban detainees from the U.S. military prison in Guantanamo Bay, Cuba, to Qatar.
"If the United States decides to transfer these detainees to Qatar, to the extent that that means that these people will be reunited with their families, the Afghan government will support it. ... but you also will have to ascertain the desire of the detainees themselves," Ludin said.
Grossman said no decision has been made about the transferring detainees from Guantanamo Bay.
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SAN FRANCISCO ? Tablets and e-readers were a popular gift over the holidays, so much so that the number of people who own them nearly doubled between mid-December and January, a new study finds.
A report from the Pew Internet and American Life Project set to be released Monday found that 29 percent of Americans owned at least one tablet or e-reader as of the beginning of this month. That's up from 18 percent who said the same in December.
The iPad from Apple Inc. is perhaps the best-known example of these gadgets, along with Amazon.com's various Kindle devices and the Nook from Barnes and Noble. The iPad put tablets on the map and the cheaper Kindle Fire and Nook devices helped get them in the hands of more people.
The percentage of people who own a tablet jumped to 19 from 10 between mid-December and early January. E-book reader ownership also rose to 19 percent from 10 percent of U.S. adults.
Men and women were equally likely to own tablets, and the likelihood of tablet ownership was higher for people with higher household incomes, the report found. Those with higher levels of education were also more likely to own tablets than those who completed fewer years of school.
E-readers, meanwhile, were slightly more common among women.
The figures are from ongoing surveys conducted by Pew about tablet and e-reader ownership. They were conducted between November 2011 and January 2012. The first, pre-holiday survey was conducted among 2,986 Americans 16 and older. Two post-holiday surveys were conducted among about 2,000 adults in January.
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KANO (Reuters) ? The death toll from gun and bomb attacks in the northern Nigerian city of Kano has risen to at least 178, a doctor in its main hospital said on Sunday, making this by far the deadliest attack claimed by the radical Islamist sect Boko Haram.
"We have 178 people killed in the two main hospitals," the senior doctor in Kano's Murtala Mohammed hospital said following Friday's attacks, citing records from his own and the other main hospital of Nasarawa.
"There could be more, because some bodies have not yet come in and others were collected early."
(Reporting by Mike Oboh; writing by Tim Cocks; editing by David Stamp)
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We've heard married people are happier, but that might not be a reason to rush to the altar, according to a new study.
In terms of health, self-esteem, and psychological well-being, marriage offers little benefit over simply living together without wedding rings, the study found.
It's the relationship itself, rather than its official status, that's key to its benefits, said study researcher Kelly Musick, an associate professor of policy analysis and management at Cornell University's College of Human Ecology.
"Being in a romantic relationship, irrespective of the legal form, does provide benefits over remaining single," Musick said.
Moreover, the findings suggest that for some, cohabitation may be the better option than marriage, Musick said. Participants who cohabited in the study were happier and had greater self-esteem than those who were married. This may be because cohabitation offers more room for independence and personal growth, which may be particularly important for some people at certain stages in life, Musick said.
The study is published in the February issue of the Journal of Marriage and Family.
Marriage vs. cohabitation
Many previous studies looking at the benefits of marriage have focused on comparing married couples with single people, or comparing married with cohabiting couples at one point in time.
The new study followed 2,737 single men and women over six years to see what happened when they entered a relationship or got married. The study data were drawn from national surveys given in the late 1980s and early 1990s.
Participants rated their overall health and happiness, and were also asked questions to assess their self -esteem, depression and the strength of their ties to friends and family.
Over the study period, close to 900 participants married or began living with a romantic partner.
In general, both marriage and cohabitation came with an uptick in well being. Those who got married or started living with a partner experienced higher levels of happiness, and lower levels of depression, than those who remained single, although these advantages faded with time.
People who married did report better overall health compared with those who cohabited, which may be explained by the entitlements (such as health insurance for spouses) that come with marriage.
However, marriage and cohabitation also reduced contact with family and friends compared to being single, and this effect lasted over time.
The researchers noted it's been about 20 years since the surveys they used were performed, and the relative benefits of marriage versus cohabitation may have changed in recent years.
However, it's not clear whether their findings would be more or less true today, Musick said. On the one hand, the experiences of marriage and cohabitation have become increasingly similar. But on the other hand, marriage may still hold a greater social status than cohabitation in the United States, she said.
Better off married?
The new findings are extremely valuable because they provide a clearer picture of the advantages of marriage, and counter the view that "marriage is the solution to so many of our problems" said Gary Lee, professor and chair department of sociology at Bowling Green State University in Ohio, who was not involved in the study. "I think that?s an incredibly naive view," Lee said.
People who claim marriage brings great benefits to everyone "are kind of cherry-picking the research," Lee said.
In reality, the people who aren't getting married may not be doing so because it won?t make them any better off, Lee said. In today's economic environment, marriage does not bring the same financial benefits as it used it, he said.
The researchers emphasized that "we are certainly not saying that marriage is irrelevant for individual well-being," Musick said. For some, marriage may be a great source of happiness.
Still, the findings call into question the value of using limited resources on campaigns to promote marriage over other family forms, Musick said. ?More research is needed to better inform policy-makers about the advantages, or lack thereof, of such campaigns.
Pass it on: Cohabitation may be just as good as marriage in promoting happiness and well-being.
This story was provided by MyHealthNewsDaily, a sister site to LiveScience. Follow MyHealthNewsDaily staff writer Rachael Rettner on Twitter @RachaelRettner. Find us on Facebook.
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Public release date: 19-Jan-2012
Share ] Contact: Ellen Weiss
eweiss@biophysics.org
240-290-5606
American Institute of Physics
Protein assassins; the biophysics of red tide blooms; how so-called "bath salts" produce a high; and a link between cigarettes and atherosclerosis are just some of the intriguing topics that will be presented at the 56th Annual Meeting of the Biophysical Society (BPS).
The conference will take place Feb. 25 - Feb. 29, 2012, at the San Diego Convention Center in San Diego, Calif. With more than 4,000 poster presentations, 200 exhibits, 20 symposia, and 6,000 research scientists in attendance each year, the Annual Meeting is the largest meeting of biophysicists in the world.
Credentialed journalists, freelance reporters working on assignment, and public information officers may attend the meeting free of charge. For more information on press registration, see below.
PRELIMINARY MEETING HIGHLIGHTS
SUNDAY, FEBRUARY 26
Microbes Help Lock Away Carbon Dioxide: As carbonate minerals form, they pull carbon dioxide out of the atmosphere, which could be an important mechanism in climate change mitigation. New research reveals the important role that microbes play in the rate of formation of carbonate minerals.
"Tuning microbial surfaces to control carbonate mineralization."
Cigarettes and Atherosclerosis: A missing link: Smoking is a significant risk factor for atherosclerosis, but the exact mechanism connecting the two is unresolved. Research hints that nicotine may trigger a remodeling of the scaffolding of cells comprising blood vessel walls, leading to plaque buildup.
"Cigarette smoke and nicotine-induced remodeling of actin cytoskeleton and extracellular matrix by vascular smooth muscle cells."
Molding the Business End of Neurotoxins: For venomous animals, the active section of a neurotoxin is the area most likely to undergo rapid evolution in response to environmental constraints, scientists find. Understanding these evolutionary forces can help researchers predict which part of unstudied toxins will do damage.
"Molding the business end of neurotoxins by diversifying evolution."
A New Approach to HIV Vaccine Design: The human immunodeficiency virus (HIV) has eluded vaccine-makers, in part due to the virus' ability to mutate rapidly. Researchers have identified collectively evolving sections of HIV that mutate in tandem, suggesting a new strategy for vaccine development.
"Analysis of collective coevolution in HIV proteins suggests strategies for rational vaccine design."
Building Complex Cell Membranes with New Layer-by-layer Technique: A new method of constructing arbitrarily complex and hitherto impossible-to-reproduce cell membranes in the lab may expand the types of cell behavior scientists can study using synthetic models.
"Layer-by-layer assembly of complex membranous cellular structures."
MONDAY, FEBRUARY 27
Crimson Tide: Mechanics of a toxin: Toxic algal blooms known as "red tides" can harm coastal bathers and marine sea life. Researchers are learning how Karenia brevis, an organism responsible for certain types of red tides, stores and releases its harmful neurotoxins.
"Exocytic mechanisms of storage and release of brevotoxin in the dinoflagellate Karenia brevis."
Synthetic Drug Known as "Bath Salts" Packs a Double Punch: New drugs that mimic illegal narcotics pose challenges for law enforcement agents attempting to combat an ever-changing target. Researchers are also attempting to keep pace by studying how these emerging compounds affect the human brain. New studies on the drug known as "bath salts" reveal that it mimics both methamphetamine and cocaine.
"Bath salts: A synthetic cathinone whose two major components act similar to methamphetamine and cocaine on the human dopamine transporter."
Texas Coral Snake's Painful Bite Decoded: The bite of the Texas coral snake produces excruciating pain in its victims, and researchers have identified how: a novel neurotoxin activates a subset of pain-sensitive nerves that normally respond to capsaicin and acid.
"A novel toxin that targets acid-sensing ion channels to produce pain."
TUESDAY, FEBRUARY 28
Proteins Behaving Badly: Researchers have developed a new way to predict which protein regions are prone to misfolding in different cellular environments. The theory may guide the design of treatments to block misfolding pathways and could help predict the progression of degenerative diseases such as ALS.
"Template-directed protein misfolding in silico and in the cell."
Alcohol Damages Heart Cells' Energy Factories: Mitochondria inside heart cells are one of the victims of alcoholism, becoming dysfunctional from excessive ethanol exposure. Scientists searching for the cause of these mitochondrial impairments studied the possibility that calcium-ion overload in the muscles of ethanol-fed rats are to blame.
"SR-Mitochondrial ultrastructure in the heart of normal and ethanol-fed rats."
Vitamins Gang up on Cancer Cells: Liver cancer is among the most vexing forms of cancer. Laboratory mouse studies reveal that combining vitamins C and K3 creates a much more toxic environment for liver cancer cells than either vitamin alone.
"On the mechanism of synergistic cytotoxicity of vitamins C and K3: Experiments in vitro and quantum-chemical analysis."
WEDNESDAY, FEBRUARY 29
Protein Assassin: Scientists find that the unfolded end of a protein can kill selectively, binding to receptor proteins found only in E. coli-like bacteria and causing the bacteria's inner membranes to spring lethal leaks.
"Targeted killing of Escherichia coli by an unfolded protein."
Potential Target for Alzheimer's Therapy: Microglia, the major inflammatory cells of the brain, play a pivotal role in the initiation and progression of Alzheimer's disease. Researchers propose that microglia may present a novel pharmacological target for curbing the harmful effects of amyloid-beta.
"Microglial KV1.3 channels as a potential target for Alzheimer's disease."
Fighting Fat: The chemical compound ShK-186 may be able to alter muscle metabolism in mice, hinting at potential therapeutic uses in the fight against obesity.
"Anti-obesity effect of SHK-186, a K+ channel blocker."
Fatigue Failure at the Molecular Level: Scientists strive to develop a theory that explains why repeated forces cause materials to fail on the molecular level. The work could help inform the design of molecule-sized machines.
"Fatigue at the molecular scale."
Building a Biological Pacemaker: By adding a protein that helps control gene expression, researchers coaxed mouse embryonic stem cells to preferentially grow into cardiac pacemaker cells. The results may lay the groundwork for future development of biological pacemakers.
"Enhanced embryonic stem cell differentiation to cardiac pacemaker cells by transduction with a single transcription factor."
ABOUT THE 2012 ANNUAL MEETING
Each year, the Biophysical Society Annual Meeting brings together over 6,000 research scientists in the multidisciplinary fields representing biophysics. With more than 4,000 poster presentations, over 200 exhibits, and more than 20 symposia, the Annual Meeting is the largest meeting of biophysicists in the world. Despite its size, the meeting retains its small-meeting flavor through its subgroup meetings, platform sessions, social activities, and committee programs.
The 56th Annual meeting will be held at the San Diego Convention Center (111 W. Harbor Drive, San Diego, CA 92101), located 3 miles from the San Diego International Airport and less than one mile from the Amtrak Station. The San Diego Trolley has two stops directly in front of the Center at Harbor Drive/First Avenue and Harbor Drive/Fifth Avenue.
###
QUICK LINKS
Meeting Home Page: http://www.biophysics.org/2012meeting/Main/tabid/2386/Default.aspx
Housing and Travel Information: http://www.biophysics.org/2012meeting/AccommodationsTravel/HotelInformation/tabid/2479/Default.aspx
Program Abstracts and Itinerary Planner: http://www.abstractsonline.com/plan/start.aspx?mkey=%7B5B4BAD87%2D5B6D%2D4994%2D84CE%2DB3B13E2AEAA3%7D
PRESS REGISTRATION
The Biophysical Society invites credentialed journalists, freelance reporters working on assignment, and public information officers to attend its Annual Meeting free of charge. For more information on registering as a member of the press, contact BPS Director of Public Affairs and Communications Ellen Weiss at eweiss@biophysics.org or 240-290-5606, or visit http://www.biophysics.org/2012meeting/Registration/Press/tabid/2477/Default.aspx.
ABOUT BPS
The Biophysical Society (BPS), founded in 1956, is a professional scientific society established to encourage development and dissemination of knowledge in biophysics. The Society promotes growth in this expanding field through its annual meeting, monthly journal, and committee and outreach activities. Its 9000 members are located throughout the U.S. and the world, where they teach and conduct research in colleges, universities, laboratories, government agencies, and industry. For more information on the Society or the 2012 Annual Meeting, visit www.biophysics.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 19-Jan-2012 Share ] Contact: Ellen Weiss
eweiss@biophysics.org
240-290-5606
American Institute of Physics
Protein assassins; the biophysics of red tide blooms; how so-called "bath salts" produce a high; and a link between cigarettes and atherosclerosis are just some of the intriguing topics that will be presented at the 56th Annual Meeting of the Biophysical Society (BPS).
The conference will take place Feb. 25 - Feb. 29, 2012, at the San Diego Convention Center in San Diego, Calif. With more than 4,000 poster presentations, 200 exhibits, 20 symposia, and 6,000 research scientists in attendance each year, the Annual Meeting is the largest meeting of biophysicists in the world.
Credentialed journalists, freelance reporters working on assignment, and public information officers may attend the meeting free of charge. For more information on press registration, see below.
PRELIMINARY MEETING HIGHLIGHTS
SUNDAY, FEBRUARY 26
Microbes Help Lock Away Carbon Dioxide: As carbonate minerals form, they pull carbon dioxide out of the atmosphere, which could be an important mechanism in climate change mitigation. New research reveals the important role that microbes play in the rate of formation of carbonate minerals.
"Tuning microbial surfaces to control carbonate mineralization."
Cigarettes and Atherosclerosis: A missing link: Smoking is a significant risk factor for atherosclerosis, but the exact mechanism connecting the two is unresolved. Research hints that nicotine may trigger a remodeling of the scaffolding of cells comprising blood vessel walls, leading to plaque buildup.
"Cigarette smoke and nicotine-induced remodeling of actin cytoskeleton and extracellular matrix by vascular smooth muscle cells."
Molding the Business End of Neurotoxins: For venomous animals, the active section of a neurotoxin is the area most likely to undergo rapid evolution in response to environmental constraints, scientists find. Understanding these evolutionary forces can help researchers predict which part of unstudied toxins will do damage.
"Molding the business end of neurotoxins by diversifying evolution."
A New Approach to HIV Vaccine Design: The human immunodeficiency virus (HIV) has eluded vaccine-makers, in part due to the virus' ability to mutate rapidly. Researchers have identified collectively evolving sections of HIV that mutate in tandem, suggesting a new strategy for vaccine development.
"Analysis of collective coevolution in HIV proteins suggests strategies for rational vaccine design."
Building Complex Cell Membranes with New Layer-by-layer Technique: A new method of constructing arbitrarily complex and hitherto impossible-to-reproduce cell membranes in the lab may expand the types of cell behavior scientists can study using synthetic models.
"Layer-by-layer assembly of complex membranous cellular structures."
MONDAY, FEBRUARY 27
Crimson Tide: Mechanics of a toxin: Toxic algal blooms known as "red tides" can harm coastal bathers and marine sea life. Researchers are learning how Karenia brevis, an organism responsible for certain types of red tides, stores and releases its harmful neurotoxins.
"Exocytic mechanisms of storage and release of brevotoxin in the dinoflagellate Karenia brevis."
Synthetic Drug Known as "Bath Salts" Packs a Double Punch: New drugs that mimic illegal narcotics pose challenges for law enforcement agents attempting to combat an ever-changing target. Researchers are also attempting to keep pace by studying how these emerging compounds affect the human brain. New studies on the drug known as "bath salts" reveal that it mimics both methamphetamine and cocaine.
"Bath salts: A synthetic cathinone whose two major components act similar to methamphetamine and cocaine on the human dopamine transporter."
Texas Coral Snake's Painful Bite Decoded: The bite of the Texas coral snake produces excruciating pain in its victims, and researchers have identified how: a novel neurotoxin activates a subset of pain-sensitive nerves that normally respond to capsaicin and acid.
"A novel toxin that targets acid-sensing ion channels to produce pain."
TUESDAY, FEBRUARY 28
Proteins Behaving Badly: Researchers have developed a new way to predict which protein regions are prone to misfolding in different cellular environments. The theory may guide the design of treatments to block misfolding pathways and could help predict the progression of degenerative diseases such as ALS.
"Template-directed protein misfolding in silico and in the cell."
Alcohol Damages Heart Cells' Energy Factories: Mitochondria inside heart cells are one of the victims of alcoholism, becoming dysfunctional from excessive ethanol exposure. Scientists searching for the cause of these mitochondrial impairments studied the possibility that calcium-ion overload in the muscles of ethanol-fed rats are to blame.
"SR-Mitochondrial ultrastructure in the heart of normal and ethanol-fed rats."
Vitamins Gang up on Cancer Cells: Liver cancer is among the most vexing forms of cancer. Laboratory mouse studies reveal that combining vitamins C and K3 creates a much more toxic environment for liver cancer cells than either vitamin alone.
"On the mechanism of synergistic cytotoxicity of vitamins C and K3: Experiments in vitro and quantum-chemical analysis."
WEDNESDAY, FEBRUARY 29
Protein Assassin: Scientists find that the unfolded end of a protein can kill selectively, binding to receptor proteins found only in E. coli-like bacteria and causing the bacteria's inner membranes to spring lethal leaks.
"Targeted killing of Escherichia coli by an unfolded protein."
Potential Target for Alzheimer's Therapy: Microglia, the major inflammatory cells of the brain, play a pivotal role in the initiation and progression of Alzheimer's disease. Researchers propose that microglia may present a novel pharmacological target for curbing the harmful effects of amyloid-beta.
"Microglial KV1.3 channels as a potential target for Alzheimer's disease."
Fighting Fat: The chemical compound ShK-186 may be able to alter muscle metabolism in mice, hinting at potential therapeutic uses in the fight against obesity.
"Anti-obesity effect of SHK-186, a K+ channel blocker."
Fatigue Failure at the Molecular Level: Scientists strive to develop a theory that explains why repeated forces cause materials to fail on the molecular level. The work could help inform the design of molecule-sized machines.
"Fatigue at the molecular scale."
Building a Biological Pacemaker: By adding a protein that helps control gene expression, researchers coaxed mouse embryonic stem cells to preferentially grow into cardiac pacemaker cells. The results may lay the groundwork for future development of biological pacemakers.
"Enhanced embryonic stem cell differentiation to cardiac pacemaker cells by transduction with a single transcription factor."
ABOUT THE 2012 ANNUAL MEETING
Each year, the Biophysical Society Annual Meeting brings together over 6,000 research scientists in the multidisciplinary fields representing biophysics. With more than 4,000 poster presentations, over 200 exhibits, and more than 20 symposia, the Annual Meeting is the largest meeting of biophysicists in the world. Despite its size, the meeting retains its small-meeting flavor through its subgroup meetings, platform sessions, social activities, and committee programs.
The 56th Annual meeting will be held at the San Diego Convention Center (111 W. Harbor Drive, San Diego, CA 92101), located 3 miles from the San Diego International Airport and less than one mile from the Amtrak Station. The San Diego Trolley has two stops directly in front of the Center at Harbor Drive/First Avenue and Harbor Drive/Fifth Avenue.
###
QUICK LINKS
Meeting Home Page: http://www.biophysics.org/2012meeting/Main/tabid/2386/Default.aspx
Housing and Travel Information: http://www.biophysics.org/2012meeting/AccommodationsTravel/HotelInformation/tabid/2479/Default.aspx
Program Abstracts and Itinerary Planner: http://www.abstractsonline.com/plan/start.aspx?mkey=%7B5B4BAD87%2D5B6D%2D4994%2D84CE%2DB3B13E2AEAA3%7D
PRESS REGISTRATION
The Biophysical Society invites credentialed journalists, freelance reporters working on assignment, and public information officers to attend its Annual Meeting free of charge. For more information on registering as a member of the press, contact BPS Director of Public Affairs and Communications Ellen Weiss at eweiss@biophysics.org or 240-290-5606, or visit http://www.biophysics.org/2012meeting/Registration/Press/tabid/2477/Default.aspx.
ABOUT BPS
The Biophysical Society (BPS), founded in 1956, is a professional scientific society established to encourage development and dissemination of knowledge in biophysics. The Society promotes growth in this expanding field through its annual meeting, monthly journal, and committee and outreach activities. Its 9000 members are located throughout the U.S. and the world, where they teach and conduct research in colleges, universities, laboratories, government agencies, and industry. For more information on the Society or the 2012 Annual Meeting, visit www.biophysics.org.
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Source: http://www.eurekalert.org/pub_releases/2012-01/aiop-mib011812.php
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